Top 40 Hits of Early October 1988
 | 1 | U2 | Desire |
 | 2 | The Hollies | He Ain't Heavy, He's My Brother |
| 3 | Whitney Houston | One Moment In Time |
| 4 | Phil Collins | Groovy Kind Of Love |
| 5 | Womack & Womack | Teardrops |
| 6 | Jason Donovan | Nothing Can Divide Us |
| 7 | Rick Astley | She Wants To Dance With Me |
| 8 | Bill Withers | Lovely Day |
| 9 | Bobby McFerrin | Don't Worry, Be Happy |
| 10 | Pet Shop Boys | Domino Dancing |
| 11 | Inner City featuring Kevin Saunderson | Big Fun |
| 12 | Erasure | A Little Respect |
| 13 | The Pasadenas | Riding On A Train |
| 14 | The Proclaimers | I'm Gonna Be |
 | 15 | Wee Papa Girl Rappers | Wee Rule |
| 16 | Duran Duran | I Don't Want Your Love |
| 17 | Yello | The Race |
| 18 | Alexander O'Neal | Fake '88 |
| 19 | Gloria Estefan & Miami Sound Machine | Anything For You |
 | 20 | Bon Jovi | Bad Medicine |
| 21 | Bros | I Quit |
| 22 | Yazz & The Plastic Population | The Only Way Is Up |
| 23 | Hazell Dean | Turn It Into Love |
| 24 | T'Pau | Secret Garden |
| 25 | Bananarama | Love Truth And Honesty |
| 26 | The Commodores | Easy |
| 27 | Salt-N-Pepa featuring EU | Shake Your Thang (It's Your Thing) |
| 28 | Kim Wilde | Never Trust A Stranger |
| 29 | TheThe Beatmasters With PP Arnold | Burn It Up |
| 30 | Bomb The Bass | Megablast / Don't Make Me Wait |
| 31 | Sinitta | I Don't Believe In Miracles |
| 32 | Brother Beyond | The Harder I Try |
| 33 | Transvision Vamp | Revolution Baby |
| 34 | Jane Wiedlin | Rush Hour |
| 35 | Coldcut featuring Junior Reid | Stop This Crazy Thing |
| 36 | Spear Of Destiny | So In Love With You |
| 37 | Sabrina | All Of Me |
| 38 | Julian Cope | Charlotte Anne |
| 39 | Marc Almond | Tears Run Rings |
| 40 | Michael Jackson | Another Part Of Me |
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